Department of Chemistry

Lund University

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"Stability of supported aerosol-generated nanoparticles in liquid media" Franzen, S.; Tasic, M.; Poulie, C.; Magnusson, M.; Strand, D.*; Messing, M.*, Sci. Rep. 2021, 11:9276 [Link] 

"A Unifying Bioinspired Synthesis of (−)-Asperaculin A and (−)-Penifulvin D.George, I. R.; López-Tena, M.; Sundin, A. P.; Strand, D.* Org. Lett.  2021, asap. [Link]

"Microsecond Photoluminescence and Photoreactivity of a Metal-Centered Excited State in a Hexacarbene–Co(III) Complex" Kaufhold, S.; Rosemann, N.W.; Chábera, P.; Lindh, L.; Losada, I.B.; Uhlig, J.; Pascher, T.; Strand, D.; Wärnmark, K.;  Yartsev, A.; Persson, P. J. Am. Chem. Soc  2021, 43, 3, 1307–1312. [Link]


"Identification of epi-enprioline as a novel drug for the treatment of  chemoresistant neuroblastoma" Sime, W.; Jema, M.; Abassi, Y.; Lasorsa, V.A.; Køhler, J.B.; Hansson, K.; Bexell, D.; Michaelis, M.; Cinatl, M.; Strand, D.; Capasso M.; Massoumi, R. Int. J. Mol. Sci.2020, in press.

"Mono endo-6- and bis endo,endo-12-N,N-diethylcarbamoyl derivatives of Tröger’s Base. Synthesis and exo-endo isomerization study" Dawaigher, S.; Lindbäck, E.; Strand, D.; Cederbalk, A.; Winikoff, S.; Harmata, M.; Snieckus, V.; Wärnmark, K. ARKIVOC, 2020, in press [link].

"A Stable Homoleptic Organometallic Iron(IV) Complex" Wärnmark, K.; Prakash, Om; Chábera, P.; Rosemann, N.W.; Huang, P.; Häggström, L.; Ericsson, T.; Strand, D.; Persson, P.; Bendix, J.; Lomoth, R. Chem. Eur. J. 2020, in press. [link]

"Enantiotopic Discrimination by Coordination‐Desymmetrized meso‐Ligands" Li , Y.; Lidskog, A.; Armengol-Relats, H.; Pham, T. H.;  Favraud, A.;  Nicolas, M.;  Dawaigher, S.;  Xiao, Z.;  Ma, D.;  Lindbäck, E.;  Strand, D.*  Wärnmark. K.* ChemCatChem. 2020, in press. [link]


"Luminescence and reactivity of a charge-transfer excited iron complex with nanosecond lifetime" Skov Kjær, K.; Kaul, N.; Prakash, O.; Chábera, P.; Rosemann, N.W.;  Honarfar, A.; Gordivska, O.; Fredin, L.A.; Bergquist, K.E.;  Häggström, L.; Ericsson, T.; Lindh, L.; Yartsev, A.; Styring, S.; Huang, P.; Uhlig, J.; Bendix, J.; Strand, D.; Sundström, V.; Persson, P.; Lomoth, R.; Wärnmark, K. Science. 2019, 6424, 249-253. [link]


"The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin" Huang, X.; Borgström, B.; Stegmayr, J.; Abassi, Y.; Kruszyk, M.; Leffler, H.; Persson, L.; Albinsson, S.; Massoumi, R.; Scheblykin, I.G.; Hegardt, C.; Oredsson, S.*; Strand, D.* ACS Centr. Sci. 20184, 760–767. [OA link]

"Control of enantioselectivity in rhodium(I)-catalysis by planar chiral dibenzo[a,e]cyclooctatetraenes" Melcher, M.; Ivsic, T.; Olagnon, C.; Tenten, C.; Lutzen, A.; Strand, D.* Chem. Eur. J. 201824, 2344-2348. [link][SYNFACTS]

"Chiral discrimination in rhodium(I) catalysis by 2,5-disubstituted 1,3a,4,6a-tetrahydropenatalene ligands – more than just a twist of the olefins?" Melcher, M.-C.; Rolim Alves da Silva, B.; Ivšić, T.; Strand, D.* ACS Omega, 2018, 3, 3622–3630. [OA link]

"Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo" Antoszczak, M. Urbaniak, A.; Delgado, M.; Ewa Maj, E.; Borgström, B.; Wietrzyk, J.; Huczyński, A.; Yuan, Y.; Chambers, T. C.; Strand, D. Eur. J. Med. Chem. 2018156, 510–523. [link]

"Semi-synthetic salinomycin analogs exert cytotoxic activity against human colorectal cancer stem cells" Klose, J.; Kattner, S.; Borgström, B.; Volz, C.; Schmidt, T.; Schneider, M.; Oredsson, S.; Strand, S.; Ulrich, A. Biochem. Biophys. Res. Commun. 2018, 459, 53-59. [link].


"Structure-Activity Relationships in Salinomycin: Cytotoxicity and Phenotype Selectivity of Semi-synthetic Derivatives" Borgström, B.; Huang, X.; Hegardt, C.; Oredsson, S.; Strand, D.* Chem. Eur. J. 201723, 2077–2083. [link][OA]

"Influence of Salinomycin Treatment on Division and Movement of Individual Cancer Cells Cultured in Normoxia or Hypoxia Evaluated with Time-Lapse Digital Holographic Microscopy" Kamlund, S.; Strand, D.; Janicke, B; Kersti, A.; Oredsson, S. Cell Cycle 2017, 16, 2128-2138. [link]

"Hydroxylated oxanes as xyloside analogs for determination of the minimal binding requirements of β4GalT7" Thorsheim, K.; Clementson, S.; Tykesson, E.; Bengtsson, D.; Strand, D.; Ellervik, U. Tetrahedron Lett. 2017, 35, 3466-3469. [link]

"Bivalent polyether ionophores: synthesis and biological evaluation of C2-symmetric salinomycin dimers" Antoszczak, M.*; Maj, E.; Borgström,B.; Oredssond, S.; Huczyński, A.; Wietrzyk, J.; Strand, D.* Tetrahedron Lett. 2017, 24, 2396-2399. [link]




"Salinomycin hydroxamic acids: synthesis, structure, and biological activity of polyether ionophore hybrids" Borgström, B.; Huang, X.; Chygorin, C.; Hegardt, C.; Oredsson, S. Strand, D.* ACS Med. Chem. Lett. 2016, 7, 635-640. [link][OA]

"Breast Cancer Stem Cell Selectivity of Nanomolar-Active Salinomycin Analogues" Huang, X.; Borgström, B.; Kempengren, S.; Persson, L.; Hegardt, C.; Strand, D.*; Oredsson, S.* BMC Cancer, 2016, 16, 145. [OA link]

"Allotwinning and OD-structures-the example of malonamide" Strand, D., Folkers, L., Lidin, S. Z. Kristallographie2016231, 623–629. [link]


"Cyclometallated gold(III) aryl-pyridine complexes as efficient catalysts for three-component synthesis of substituted oxazoles" Wachenfeldt, H v. W.; Polukeev, A. V.; Loganathan, N.; Paulsen, F.; Röse, F.; Garreau, M.; Wendt, O. F.; Strand. D.* Dalton Trans. 2015, 28, 5347–5353. [OA link]

"Iridium Catalyzed Carbocyclizations: Efficient (5+2) Cycloadditions of Vinylcyclopropanes and Alkynes" Melcher, M.; Wachenfeldt, H v. W.; Sundin, A.; Strand. D.* Chem. Eur. J. 2015, 21, 531–535. [link][OA]


"Semisynthesis of SY-1 for investigation of breast cancer stem cell selectivity of C-ring-modified salinomycin analogs" Huang, X.; Månsson, L.; Borgström, B.; Persson, L.; Oredsson, S.; Hegardt, C.; Strand, D.* ACS Chem. Biol. 2014, 9, 1587–1594. [OA link]


"Synthetic Modification of Salinomycin: Selective O-Acylation and Biological Evaluation" Borgström, B.; Huang, X.; Pošta, M.; Hegardt, C.; Oredsson, S.; Strand, D.* Chem. Commun. 201349, 9944–9946. [OA link]

"Catalytic three-component domino reaction for preparation of tri-substituted oxazoles" Wachenfeldt, H.v.; Röse, P.; Paulsen, F.; Loganathan N.; Strand, D.* Chem. Eur. J. 201319, 7982–7988. [link][OA]

"Synthesis of formylsilanes through oxidative cleavage of a-silyl glycols" Wachenfeldt, H.v.; Strand, D.* J. Org. Chem. 2013, 78, 12268–12273. [link][OA]

"Allotwinning in a molecular crystal: (1R,3S)-Dimethyl 2-oxocyclohexane-1,3-dicarboxylate" Jahangiri, A.; Fleckhaus, A.; Lidin, S.; Strand, D.* Acta Cryst B. Cryst. Eng. Mat. 2013, B69, 509–513. [OA link]

"Synthesis of Substituted Oxazoles from N-Bn Propargyl Amines and Acid Chlorides" Wachenfeldt, H.v.; Paulsen, F.; Sundin, A.; Strand, D.* Eur. J. Org. Chem. 2013, 4578–4585. [link][OA]

"(6R*,10R*)-Dimethyl-1,4-dioxaspiro[4.5]decane-6,10-dicarboxylate" Jahangiri, A.; Wendt, O.; Strand D.* Acta Cryst. E. 2013, 69, o265. [OA link]


"[(BINAP)Re(O)Cl3] as an Efficient Catalyst for Olefination of Chiral Substituted Aliphatic Aldehydes" Strand, D.*; Rein, T. J. Organomet Chem. 2010695, 2220–2224. [link]

2009 and older

"Cyclocarboamination of Alkynes with Aziridines: Synthesis of 2,3-Dihydropyrroles by a Catalyzed Formal [3 + 2] Cycloaddition", Wender, P. A.; Strand, D. J. Am. Chem. Soc. 2009, 131, 7528–7529. [link]

"Total Synthesis of Iejimalide B. An Application of the Shiina Macrolactonization", Schweitzer, D.; Kane, J. J.; Strand, D.; McHenry, P.; Tenniswood, M.; Helquist P. Org. Lett. 2007, 9, 4619–4622. [link]

"Divergence en Route to Non-classical Annonaceous Aceogenins. Total Synthesis of Pyranicin and Pyragonicin", Strand, D.; Norrby P-.O.; Rein, T. J. Org. Chem. 2006, 71, 1879–1891. [link]

"Synthesis of Pyragonicin", Strand, D.; Rein, T. Org. Lett. 2005, 7, 2779–2782. [link]

"Total Synthesis of Pyranicin", Strand, D.; Rein, T. Org. Lett. 2005, 7, 199–202. [link]


Teaching material
Strand, D. "Organic Chemistry - Theory; Experiments and Exercises", Mediatryck, Lund University, Sweden, 2010–present

Strand, D. "Methods for Asymmetric Olefination reactions; Development and Application to Natural Product Synthesis", Ph.D. Thesis, Royal Institute of Technology, Stockholm, Sweden, 2006.