Department of Chemistry

Lund University

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"Control of enantioselectivity in rhodium(I)-catalysis by planar chiral dibenzo[a,e]cyclooctatetraenes" Melcher, M.; Ivsic, T.; Olagnon, C.; Tenten, C.; Lutzen, A.; Strand, D.* Chem. Eur. J. in press [link]

"Semi-synthetic salinomycin analogs exert cytotoxic activity against human colorectal cancer stem cells" Klose, J.; Kattner, S.; Borgström, B.; Volz, C.; Schmidt, T.; Schneider, M.; Oredsson, S.; Strand, S.; Ulrich, A. Biochem. Biophys. Res. Commun.2017, in press, [link].

"Influence of Salinomycin Treatment on Division and Movement of Individual Cancer Cells Cultured in Normoxia or Hypoxia Evaluated with Time-Lapse Digital Holographic Microscopy" Kamlund, S.; Strand, D.; Janicke, B; Kersti, A.; Oredsson, S. Cell Cycle 2017, in press, [link]

"Hydroxylated oxanes as xyloside analogs for determination of the minimal binding requirements of β4GalT7" Thorsheim, K.; Clementson, S.; Tykesson, E.; Bengtsson, D.; Strand, D.; Ellervik, U. Tetrahedron Lett. 2017, 35, 3466-3469. [link]

"Bivalent polyether ionophores: synthesis and biological evaluation of C2-symmetric salinomycin dimers" Antoszczak, M.*; Maj, E.; Borgström,B.; Oredssond, S.; Huczyński, A.; Wietrzyk, J.; Strand, D.* Tetrahedron Lett. 2017, 24, 2396-2399. [link]

"Structure-Activity Relationships in Salinomycin: Cytotoxicity and Phenotype Selectivity of Semi-synthetic Derivatives" Borgström, B.; Huang, X.; Hegardt, C.; Oredsson, S.; Strand, D.* Chem. Eur J. 201723, 2077–2083. [link][OA]


"Allotwinning and OD-structures-the example of malonamide" Strand, D., Folkers, L., Lidin, S. Z. Kristallographie, 2016, 231, 623–629. [link]

"Salinomycin hydroxamic acids: synthesis, structure, and biological activity of polyether ionophore hybrids" Borgström, B.; Huang, X.; Chygorin, C.; Hegardt, C.; Oredsson, S. Strand, D.* ACS Med. Chem. Lett. 2016, 7, 635-640. [link][OA]

"Breast Cancer Stem Cell Selectivity of Nanomolar-Active Salinomycin Analogues" Huang, X.; Borgström, B.; Kempengren, S.; Persson, L.; Hegardt, C.; Strand, D.*; Oredsson, S.* BMC Cancer, 2016, 16, 145. [OA link]


"Cyclometallated gold(III) aryl-pyridine complexes as efficient catalysts for three-component synthesis of substituted oxazoles" Wachenfeldt, H v. W.; Polukeev, A. V.; Loganathan, N.; Paulsen, F.; Röse, F.; Garreau, M.; Wendt, O. F.; Strand. D.* Dalton Trans. 2015, 28, 5347–5353. [OA link]

"Iridium Catalyzed Carbocyclizations: Efficient (5+2) Cycloadditions of Vinylcyclopropanes and Alkynes" Melcher, M.; Wachenfeldt, H v. W.; Sundin, A.; Strand. D.* Chem. Eur. J. 2015, 21, 531–535. [link][OA]


"Semisynthesis of SY-1 for investigation of breast cancer stem cell selectivity of C-ring-modified salinomycin analogs" Huang, X.; Månsson, L.; Borgström, B.; Persson, L.; Oredsson, S.; Hegardt, C.; Strand, D.* ACS Chem. Biol. 2014, 9, 1587–1594. [OA link]


"Synthesis of formylsilanes through oxidative cleavage of a-silyl glycols" Wachenfeldt, H.v.; Strand, D.* J. Org. Chem. 2013, 78, 12268–12273. [link][OA]

"Synthetic Modification of Salinomycin: Selective O-Acylation and Biological Evaluation" Borgström, B.; Huang, X.; Pošta, M.; Hegardt, C.; Oredsson, S.; Strand, D.* Chem. Commun. 2013, 49, 9944–9946. [OA link]

"Allotwinning in a molecular crystal: (1R,3S)-Dimethyl 2-oxocyclohexane-1,3-dicarboxylate" Jahangiri, A.; Fleckhaus, A.; Lidin, S.; Strand, D.* Acta Cryst B. Cryst. Eng. Mat. 2013, B69, 509–513. [OA link]

"Synthesis of Substituted Oxazoles from N-Bn Propargyl Amines and Acid Chlorides" Wachenfeldt, H.v.; Paulsen, F.; Sundin, A.; Strand, D.* Eur. J. Org. Chem. 2013, 4578–4585. [link][OA]

"Catalytic three-component domino reaction for preparation of tri-substituted oxazoles" Wachenfeldt, H.v.; Röse, P.; Paulsen, F.; Loganathan N.; Strand, D.* Chem. Eur. J. 2013, 19, 7982–7988. [link][OA]

"(6R*,10R*)-Dimethyl-1,4-dioxaspiro[4.5]decane-6,10-dicarboxylate" Jahangiri, A.; Wendt, O.; Strand D.* Acta Cryst. E. 2013, 69, o265. [OA link]


"[(BINAP)Re(O)Cl3] as an Efficient Catalyst for Olefination of Chiral Substituted Aliphatic Aldehydes" Strand, D.*; Rein, T. J. Organomet Chem. 2010695, 2220–2224. [link]

2009 and older

"Cyclocarboamination of Alkynes with Aziridines: Synthesis of 2,3-Dihydropyrroles by a Catalyzed Formal [3 + 2] Cycloaddition", Wender, P. A.; Strand, D. J. Am. Chem. Soc. 2009, 131, 7528–7529. [link]

"Total Synthesis of Iejimalide B. An Application of the Shiina Macrolactonization", Schweitzer, D.; Kane, J. J.; Strand, D.; McHenry, P.; Tenniswood, M.; Helquist P. Org. Lett. 2007, 9, 4619–4622. [link]

"Divergence en Route to Non-classical Annonaceous Aceogenins. Total Synthesis of Pyranicin and Pyragonicin", Strand, D.; Norrby P-.O.; Rein, T. J. Org. Chem. 2006, 71, 1879–1891. [link]

"Synthesis of Pyragonicin", Strand, D.; Rein, T. Org. Lett. 2005, 7, 2779–2782. [link]

"Total Synthesis of Pyranicin", Strand, D.; Rein, T. Org. Lett. 2005, 7, 199–202. [link]


Teaching material
Strand, D. "Organic Chemistry - Theory; Experiments and Exercises", Mediatryck, Lund University, Sweden, 2010–present

Strand, D. "Methods for Asymmetric Olefination reactions; Development and Application to Natural Product Synthesis", Ph.D. Thesis, Royal Institute of Technology, Stockholm, Sweden, 2006.